Role of inflammation in tumorous accretion of radiopharmaceuticals: Experimental studies with 67Ga, 169Yb, 111In, 99mTc-pertechnetate, 99mTc-bleomycin 57Co-bleomycin and 198Au-colloid.
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چکیده
منابع مشابه
Sensitivity of the Limulus test and inhibitory factors in the radiopharmaceuticals.
The basic sensitivity of the Limulus test and the inhibitory factors were examined in 21 radiopharmaceuticals commonly used in Japan. The sensitivity of the Limulus test using pre-gel was found to be 1 mug/ml for Escherichia coli endotoxin. This sensitivity is about ten times that of the rabbit test adopted by USP and JP. The Limulus test was applicable, with full sensitivity and without inhibi...
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With a current annual mortality rate of around 35% worldwide, infection remains a significant concern, and the diagnosis and localization of infectious foci is an important health issue. As an established infection-imaging modality, nuclear medicine plays a vital health-care role in the diagnosis and subsequent effective treatment of this condition. Despite the development of several newer radi...
متن کاملPreparation of [111In]-Bleomycin radiopharmaceutical [Persian]
In this study, the preparation of 111In-Bleomycin complex was optimized for temperature, time, concentration and pH during several experiments. The results showed that by the addition of bleomycin to 111In-InCl3 sample (dried under flow of N2) and heating the mixture up to 90-100°C the radiopharmaceutical can be obtained in 99.5% yield and a specific activity of 1.745 Ci/mmol. The final s...
متن کامل57Co-bleomycin and 67Ga-citrate in detecting and staging lung cancer.
In the investigation of suspected lung cancer bleomycin labelled with cobalt-57 and gallium-67 labelled with citrate are currently used to detect the primary tumour and to establish the presence of metastases in the lung hilum and mediastinum. A comparative study of these radio-pharmaceuticals was performed in 63 patients with proved lung cancer. 57Co-bleomycin showed the primary tumour in 58 p...
متن کاملDouble-tracer scintigraphy with 67Ga-citrate and 99mTc-sulfur colloid in the diagnosis of hepatic tumors.
A method of liver scanning based on a subtraction technique with simultaneous use of two tracers, 67Ga-citrate and 99mTc-sulfur colloid, is described. The subtraction technique isolates radiogallium uptake by the space-occupying hepatic lesions by subtracting interference due to tracer uptake by healthy hepatic tissue. In 82 patients, the method yielded a correct result in 94.7% of the positive...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1975
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.24.6_410